NanoCelle® B12
Study Site:
Northern Cancer Institute, 38 Pacific Hwy, St Leonards, NSW, 2065Formulation:
NanoCelle® B12 is a sub-micron spray applied to the oro-buccal membrane delivering 1000 mcg in 2 actuation of the pump. The absorption characteristics of Medlab NanoCelle® B12 were compared to 6 other Vitamin B12 formulations in a Phase 0, absorption study.
About Trial:
This study assesses the vitamin B12 blood level absorption in healthy adult volunteers.
Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. Vitamin B12 deficiency is characterised by megaloblastic anemia, fatigue, weakness, constipation, loss of appetite, and weight loss. The main causes of vitamin B12 deficiency include vitamin B12 malabsorption from food, pernicious anemia, postsurgical malabsorption, and dietary deficiency.
Source: National Institutes of Health, Office of Dietary Supplements, Vitamin B12. March 2020
There is significant interest from researchers, general practitioners and the public regarding the administration of Vitamin B12 supplements for health maintenance or disease treatments. The aim of this study is to evaluate the absorption characteristics of a selected group of Australian and U.S marketed over the counter (OTC) Vitamin B12 products. As such this study purposes to evaluate the absorption characteristics of these products.
HREC Date:
2014-05-22HREC Date:
2014-05-22HREC ID:
0013EPUBLICATIONS OR CONFERENCES ASSOCIATED WITH THE PROGRAM
The 5th Annual Symposium of Drug Delivery Systems Oct 20-22, 2015. Beijing, China.
Date: 2015-10-20
Authors: Coulson S
BIT’s 14th Annual Congress of IDDST June 16-18, 2016. South Korea
Date: 2016-06-16
Authors: Hall S
Clinical Nutrition 2013; 32(6): 888-893
Date: 2013-04-15
Authors: Schloss JM,Colosimo M, Airey C, Vitetta L
Support Care Cancer 2015;23(7):1843-50
Date: 2015-07-01
Authors: Schloss J, Colosimo M, Airey C, Vitetta L
Asia-Pacific Journal of Oncology Nursing 2015; 3(1):73-85.
Date: 2016-01-01
Authors: Schloss J, Colosimo M, Vitetta L
Support Care Cancer 2016;25(1):195-204.
Date: 2017-01-02
Authors: Schloss JM, Colosimo M, Airey C, Masci P, Linnane AW, Vitetta L
Journal of Functional Biomaterials. 2018, 9(1), 12; https://doi.org/10.3390/jfb9010012
Date: 2017-12-23
Authors: Vitetta L, Zhou J, Manuel R, Dal Forno S, Hall S, Rutolo D
